• 1.

    Castagnoli, R. et al. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children and adolescents: a systematic review. JAMA Pediatr. 174, 882–889 (2020).

  • 2.

    Midulla, F. Cristiani, L. & Mancino, E. Will children reveal their secret? The coronavirus dilemma. Eur. Respir. J. 55, 2000749 (2020).

  • 3.

    Dong, Y. et al. Epidemiology of COVID-19 among children in China. Pediatrics 145, e20200702 (2020).

  • 4.

    Li, Y. et al. Insight into COVID-2019 for pediatricians. Pediatr. Pulmonol. 55, E1–E4 (2020).

    Article 

    Google Scholar
     

  • 5.

    Qiu, H. et al. Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study. Lancet Infect. Dis. 20, 689–696 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 6.

    Tagarro, A. et al. Screening and severity of coronavirus disease 2019 (COVID-19) in children in Madrid, Spain. JAMA Pediatr. https://doi.org/10.1001/jamapediatrics.2020.1346 (2020).

  • 7.

    Ding, Y., Yan, H. & Guo, W. Clinical characteristics of children with COVID-19: a meta-analysis. Front. Pediatr. 8, 431 (2020).

    Article 

    Google Scholar
     

  • 8.

    Shen, K. et al. Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts’ consensus statement. World J. Pediatr. 16, 223–231 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 9.

    Shen, K. L. & Yang, Y. H. Diagnosis and treatment of 2019 novel coronavirus infection in children: a pressing issue. World J. Pediatr. 16, 219–221 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 10.

    Chen, Z. M., Fu, J. F. & Shu, Q. New coronavirus: new challenges for pediatricians. World J. Pediatr. 16, 222 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 11.

    Society of Pediatrics, Chinese Medical Association & Editorial Board, Chinese Journal of Pediatrics. [Recommendations for the diagnosis, prevention and control of the 2019 novel coronavirus infection in children (first interim edition)]. Zhonghua Er Ke Za Zhi 58, 169–174 (2020).


    Google Scholar
     

  • 12.

    Munn, Z. et al. Methodological guidance for systematic reviews of observational epidemiological studies reporting prevalence and cumulative incidence data. Int. J. Evid. Based Health 13, 147–153 (2015).

    Article 

    Google Scholar
     

  • 13.

    Alzamora, M. C. et al. Severe COVID-19 during pregnancy and possible vertical transmission. Am. J. Perinatol. 37, 861–865 (2020).

  • 14.

    An, P. & Zhang, M. Novel coronavirus SARS-CoV-2: familial spread resulting in COVID-19 pneumonia in a pediatric patient. Diagn. Interv. Radiol. 26, 262–263 (2020).

  • 15.

    Cai, J. H. et al. [First case of 2019 novel coronavirus infection in children in Shanghai]. Zhonghua Er Ke Za Zhi 58, E002 (2020).

    CAS 
    PubMed 

    Google Scholar
     

  • 16.

    Canarutto, D. et al. COVID-19 infection in a paucisymptomatic infant: Raising the index of suspicion in epidemic settings. Pediatr. Pulmonol. 55, E4–E5 (2020).

  • 17.

    Chen, F. et al. [First case of severe childhood novel coronavirus pneumonia in China]. Zhonghua Er Ke Za Zhi 58, E005 (2020).

    CAS 
    PubMed 

    Google Scholar
     

  • 18.

    Chen, Z. et al. [COVID-19 with post-chemotherapy agranulocytosis in childhood acute leukemia: a case report]. Zhonghua Xue Ye Xue Za Zhi 41, E004 (2020).


    Google Scholar
     

  • 19.

    Cui, Y. et al. A 55-day-old female infant infected with COVID 19: presenting with pneumonia, liver injury, and heart damage. J. Infect. Dis. 221, 1775–1781 (2020).

  • 20.

    Dong, L. et al. Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn. JAMA 323, 1846–1848 (2020).

  • 21.

    Feng, K. et al. [Analysis of CT features of 15 children with 2019 novel coronavirus infection]. Zhonghua Er Ke Za Zhi 58, E007 (2020).

    CAS 
    PubMed 

    Google Scholar
     

  • 22.

    Genovese, G., Colonna, C. & Marzano, A. V. Varicella-like exanthem associated with COVID-19 in an 8-year-old girl: a diagnostic clue? Pediatr. Dermatol. 37, 435–436 (2020).

  • 23.

    Guiqing, H. E., Sun, W., Jing, W. U. & Cai, J. Serial computed tomography manifestations in a child with coronavirus disease (COVID-19) pneumonia. Indian Pediatr. 57, 467–468 (2020).

  • 24.

    Hrusak, O. et al. Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment. Eur. J. Cancer 132, 11–16 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 25.

    Ji, L. N. et al. Clinical features of pediatric patients with COVID-19: a report of two family cluster cases. World J. Pediatr. 16, 267–270 (2020).

  • 26.

    Jiang, S. et al. Coinfection of SARS-CoV-2 and multiple respiratory pathogens in children. Clin. Chem. Lab. Med. 58, 1160–1161 (2020).

  • 27.

    Kam, K. Q. et al. A well infant with coronavirus disease 2019 (COVID-19) with high viral load. Clin. Infect. Dis. 71, 847–849 (2020).

  • 28.

    Kamali Aghdam, M., Jafari, N. & Eftekhari, K. Novel coronavirus in a 15-day-old neonate with clinical signs of sepsis, a case report. Infect. Dis. 52, 427–429 (2020).

    Article 

    Google Scholar
     

  • 29.

    Kan, M. J., Grant, L. M. C., Muna, M. A. & Greenhow, T. L. Fever without a source in a young infant due to SARS-CoV-2. J. Pediatric Infect. Dis. Soc. 10, 49–51 (2020).

  • 30.

    Li, W. et al. Chest computed tomography in children with COVID-19 respiratory infection. Pediatr. Radiol. 50, 796–799 (2020).

  • 31.

    Lin, J. et al. The isolation period should be longer: lesson from a child infected with SARS-CoV-2 in Chongqing, China. Pediatr. Pulmonol. 55, E6–E9 (2020).

  • 32.

    Liu, H. et al. Clinical and CT imaging features of the COVID-19 pneumonia: focus on pregnant women and children. J. Infect. 80, e7–e13 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 33.

    Liu, M., Song, Z. & Xiao, K. High-resolution computed tomography manifestations of 5 pediatric patients with 2019 novel coronavirus. J. Comput. Assist. Tomogr. 44, 311–313 (2020).

  • 34.

    Liu, W. et al. Detection of Covid-19 in children in early January 2020 in Wuhan, China. N. Engl. J. Med. 382, 1370–1371 (2020).

    Article 

    Google Scholar
     

  • 35.

    Paret, M. et al. SARS-CoV-2 infection (COVID-19) in febrile infants without respiratory distress. Clin. Infect. Dis. 71, 2243–-2245 (2020).

  • 36.

    Park, J. Y. et al. First pediatric case of coronavirus disease 2019 in Korea. J. Korean Med. Sci. 35, e124 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 37.

    Qian, G. et al. A COVID-19 transmission within a family cluster by presymptomatic infectors in China. Clin. Infect. Dis. 71, 861–862 (2020).

  • 38.

    See, K. C. et al. COVID-19: four paediatric cases in Malaysia. Int. J. Infect. Dis. 94, 124–127 (2020).

  • 39.

    Shen, Q. et al. Novel coronavirus infection in children outside of Wuhan, China. Pediatr. Pulmonol. 55, 1424–1429 (2020).

  • 40.

    Su, L. et al. The different clinical characteristics of corona virus disease cases between children and their families in China – the character of children with COVID-19. Emerg. Microbes Infect. 9, 707–713 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 41.

    Song, R. et al. Clinical and epidemiological features of COVID-19 family clusters in Beijing, China. J. Infect. 81, e26–e30 (2020).

  • 42.

    Zhu, L. et al. Clinical characteristics of a case series of children with coronavirus disease 2019. Pediatr. Pulmonol. 55, 1430–1432 (2020).

  • 43.

    Zhou, Y. et al. [Clinical features and chest CT findings of coronavirus disease 2019 in infants and young children]. Zhongguo Dang Dai Er Ke Za Zhi 22, 215–220 (2020).

    PubMed 

    Google Scholar
     

  • 44.

    Zhang, Z. J. et al. Novel coronavirus infection in newborn babies under 28 days in China. Eur. Respir. J. 55, 2000697 (2020).

  • 45.

    Zhang, T. et al. Detectable SARS-CoV-2 viral RNA in feces of three children during recovery period of COVID-19 pneumonia. J. Med. Virol. 92, 909–914 (2020).

  • 46.

    Zhang, G. X. et al. [Twin girls infected with SARS-CoV-2]. Zhongguo Dang Dai Er Ke Za Zhi 22, 221–225 (2020).

    PubMed 

    Google Scholar
     

  • 47.

    Zhang, B. et al. Positive rectal swabs in young patients recovered from coronavirus disease 2019 (COVID-19). J. Infect. 81, e49–e52 (2020).

  • 48.

    Zeng, L. K. et al. [First case of neonate with COVID-19 in China]. Zhonghua Er Ke Za Zhi 58, 289–280 (2020).


    Google Scholar
     

  • 49.

    Zeng, L. et al. Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China. JAMA Pediatr. 174, 722–725 (2020).

  • 50.

    Yu, N. et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet Infect. Dis. 20, 559–564 (2020).

  • 51.

    Xu, Y. et al. Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding. Nat. Med. 26, 502–505 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 52.

    Xu, R. et al. CT imaging of one extended family cluster of corona virus disease 2019 (COVID-19) including adolescent patients and “silent infection”. Quant. Imaging Med. Surg. 10, 800–804 (2020).

    Article 

    Google Scholar
     

  • 53.

    Wu, P., Liang, L., Chen, C. & Nie, S. A child confirmed COVID-19 with only symptoms of conjunctivitis and eyelid dermatitis. Graefes Arch. Clin. Exp. Ophthalmol. 258, 1565–1566 (2020).

  • 54.

    Wei, M. et al. Novel coronavirus infection in hospitalized infants under 1 year of age in China. JAMA 323, 1313–1314 (2020).

  • 55.

    Wang, S. et al. A case report of neonatal COVID-19 infection in China. Clin. Infect. Dis. 71, 853–857 (2020).

  • 56.

    Wang, J. et al. [SARS-CoV-2 infection with gastrointestinal symptoms as the first manifestation in a neonate]. Zhongguo Dang Dai Er Ke Za Zhi 22, 211–214 (2020).

    PubMed 

    Google Scholar
     

  • 57.

    Wang, H. et al. Rehospitalization of a recovered coronavirus disease 19 (COVID-19) child with positive nucleic acid detection. Pediatr. Infect. Dis. J. 39, e69–e70 (2020).

  • 58.

    Tang, A. et al. Detection of novel coronavirus by RT-PCR in stool specimen from asymptomatic child, China. Emerg. Infect. Dis. 26, 1337–1339 (2020).

  • 59.

    Tan, Y. P. et al. Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China. J. Clin. Virol. 127, 104353 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 60.

    Tan, X. et al. [Clinical features of children with SARS-CoV-2 infection: an analysis of 13 cases from Changsha, China]. Zhongguo Dang Dai Er Ke Za Zhi 22, 294–298 (2020).

    PubMed 

    Google Scholar
     

  • 61.

    Sun, D. et al. Clinical features of severe pediatric patients with coronavirus disease 2019 in Wuhan: a single center’s observational study. World J. Pediatr. 16, 251–259 (2020).

  • 62.

    Xing, Y. H. et al. Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019. J. Microbiol. Immunol. Infect. 53, 473–480 (2020).

  • 63.

    Zheng, F. et al. Clinical characteristics of children with coronavirus disease 2019 in Hubei, China. Curr. Med. Sci. 40, 275–280 (2020).

  • 64.

    Li, Y. et al. Immune-related factors associated with pneumonia in 127 children with coronavirus disease 2019 in Wuhan. Pediatr. Pulmonol. 55, 2354–2360 (2020).

  • 65.

    Abdel-Mannan, O. et al. Neurologic and radiographic findings associated with COVID-19 infection in children. JAMA Neurol. 77, 1–6 (2020).

  • 66.

    Epidemiology Working Group for NCIP Epidemic Response, Chinese Center for Disease Control and Prevention. [The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China]. Zhonghua Liu Xing Bing Xue Za Zhi 41, 145–151 (2020).


    Google Scholar
     

  • 67.

    Wang, Z. et al. Clinical characteristics of children with COVID-19: a rapid review and meta-analysis. Ann. Transl. Med. 8, 620 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 68.

    Chen, G. et al. Clinical and immunological features of severe and moderate coronavirus disease 2019. J. Clin. Invest. 130, 2620–2629 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 69.

    Li, X. et al. Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan. J. Allergy Clin. Immunol. 146, 110–118 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 70.

    Wu, C. et al. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA Intern. Med. 180, 934–943 (2020).

  • 71.

    Ludvigsson, J. F. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr. 109, 1088–1095 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 72.

    Wrapp, D. et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 367, 1260–1263 (2020).

    CAS 
    Article 

    Google Scholar
     

  • 73.

    Simon, A. K., Hollander, G. A. & McMichael, A. Evolution of the immune system in humans from infancy to old age. Proc. Biol. Sci. 282, 20143085 (2015).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 74.

    Henry, B. M., Lippi, G. & Plebani, M. Laboratory abnormalities in children with novel coronavirus disease 2019. Clin. Chem. Lab. Med. 58, 1135–1138 (2020).

    CAS 
    Article 

    Google Scholar
     



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